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BREAST CANCER: CAUSES, SYMPTOMS, DIAGNOSIS AND HERBAL TREATMENT
By stephany On 08/05/2020
Over the past 20 years, the incidence of breast cancer has doubled. Women die more often from this disease than from all other oncological diseases. These are the annual statistics of deaths from breast cancer. In most of these patients, the disease was detected late, incompatible with life. Even with all the efforts of doctors. An increase in the incidence of breast cancer is observed worldwide. About 1 million women fall ill every year in the world.
The female breast is a glandular organ that, during the period of the baby’s birth, has an important function of milk production and feeding. Young mothers do not always skillfully process and care for their breasts and for this reason they often encounter problems.
Of course, improper hygiene during feeding is not always the cause of the development of pathology, but this is one of the factors in the development of benign dysfunctions and gland seals:
- Mastopathy is characterized by the presence of many knotty seals in the tissue.
- Mastitis is an inflammatory disease of the glandular tissue and ducts of the gland (purulent, serous)
- Fibroadenoma is a benign tumor in the tissues of the mammary gland, consisting, as a rule, of fibrous connective tissue. Any of these pathologies can be confused with the onset of the oncological process.
What is breast cancer?
Breast cancer is an uncontrolled growth of breast cells. To better understand breast cancer, it helps to understand how any cancer can develop.
Cancer occurs as a result of mutations, or abnormal changes, in the genes responsible for regulating the growth of cells and keeping them healthy. The genes are in each cell’s nucleus, which acts as the “control room” of each cell. Normally, the cells in our bodies replace themselves through an orderly process of cell growth: healthy new cells take over as old ones die out. But over time, mutations can “turn on” certain genes and “turn off” others in a cell. That changed cell gains the ability to keep dividing without control or order, producing more cells just like it and forming a tumor.
A tumor can be benign (not dangerous to health) or malignant (has the potential to be dangerous). Benign tumors are not considered cancerous: their cells are close to normal in appearance, they grow slowly, and they do not invade nearby tissues or spread to other parts of the body. Malignant tumors are cancerous. Left unchecked, malignant cells eventually can spread beyond the original tumor to other parts of the body.
The term “breast cancer” refers to a malignant tumor that has developed from cells in the breast. Usually breast cancer either begins in the cells of the lobules, which are the milk-producing glands, or the ducts, the passages that drain milk from the lobules to the nipple. Less commonly, breast cancer can begin in the stromal tissues, which include the fatty and fibrous connective tissues of the breast.
HERBAL TREATMENT FOR BREAST CANCER
We offer here a mixture of seeds, roots and bark from Africa which prevent and cure all kinds of cancer (breast cancer, cancer of the liver, prostate cancer, thyroid cancer, cervical cancer uterus, kidney cancer, ovarian cancer) and cardiovascular disease. These plants are very little known to scientists and they have extraordinary qualities against cancer. Their use against cancer is much more effective than chemotherapy.
The objective of this treatment is to;
- Fighting cancer cells.
- To prevent cancer cells from spreading to other organs.
- To strengthen the body's defense against other diseases by strengthening the immune system.
- To increase the effect of chemotherapy and radiotherapy.
- To reduce side effects such as dizziness, headache, nausea, vomiting and weakness from illness, chemotherapy or radiotherapy.
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WHAT CAUSES BREAST CANCER?
- A cancerous tumor
It develops inside our body, from our own cells, which for some reason have mutated. Scientists all over the world have been struggling with the cause of cancer for several decades and come to the conclusion that the destructive mechanism of the disease triggers not one, but many factors.
Various factors play a role in the occurrence of breast cancer. The early onset of menstruation - up to 12 pet - is unfavorable, as is the late onset after 55 years. Of fundamental importance is the reproductive function - if the first birth in 30 pet is unfavorable, after 40 it is already a risk group.
The female breast should fulfill all the functions assigned to it by nature. Namely, to feed children. The longer the lactation period, the lower the risk of breast cancer.
Sexual function per se is of fundamental importance: lack of sex life, later onset after 25-30 years, methods of contraception are also important. A woman should consult with a gynecologist - mechanical methods are especially unacceptable for women who are prone to the occurrence of hormone-borne diseases that contribute to the onset of a tumor.
Cancer is associated with metabolic disorders in the body of a woman. Overweight, obesity, diabetes mellitus - a list of negative factors also complement arterial hypertension and atherosclerosis, severe liver and thyroid diseases.
- Mastopathy
This belongs to the category of benign dishormonal diseases. They suffer a large number of women. It is believed that every second woman suffers from dishormonal disease. In fact, this is not so, it’s just that sometimes they are mistaken for the usual swelling of the mammary glands as a physiological factor before menstruation. Dyshormonal diseases are usually associated with impaired hormone metabolism associated with ovarian function, the period of their occurrence is from 25 years.
A tumor does not occur out of the blue. Development is preceded by changes in the mammary gland. Diffuse mastopathy is a background condition that can develop into a focal one. Patients should be observed by gynecologists, with some changes, surgical treatment is needed - the focus of mastopathy is cut out. There is another disease - intraductal papilloma. Symptoms are blood from the nipple, and surgery is also needed here. This is a cancer warning - the identification of precancerous diseases and their treatment.
WHAT ARE THE SIGNS OF THIS PATHOLOGY?
- Perhaps the presence of pain.
- A visual inspection reveals a clear asymmetry and a change in shape.
- In the halo area, ulceration, peeling, or crusting may be present.
- Sensation of pain in the armpit (regional lymph nodes)
- Discharge from the nipple (provided that you are not a nursing mother) of a different nature, especially bloody
- Hyperemia of the skin and swelling. All these symptoms indicate a terrible cancer. If you find at least one of these symptoms during an independent examination, do not delay visiting a doctor. Diagnosis of breast cancer: how to determine breast cancer?
DIAGNOSTIC METHODS OF BREAST CANCER
Up to 45 years, a woman should undergo an ultrasound every year, after which a mammogram is recommended. Glandular tissue is denser than fatty tissue, and after 45 years it turns into fatty tissue and radiation is retained in this tissue. As an early diagnosis after 45 years, mammography is recommended to all women once a year. Depending on the structure of the mammary gland, a re-examination after 1.5-2 years or after 6 months.
There are risk groups for women who need to examine the mammary glands, primarily women with a hereditary predisposition, with precancerous conditions and benign tumors.
- Mammography allows you to clearly determine the malignant potential of the tumor and identify its smallest foci.
- Ultrasound is a more harmless and affordable method than x-ray examination. It can be performed on a woman of any age, an unlimited number of times. Ultrasound can distinguish benign mammary glands, reveal a malignant tumor, but does not see a microcarcinoma. Ultrasound is recommended for women under 35 years old - a detection rate of 87%. The combination of mammography and ultrasound gives almost 100% detection. Ultrasound is also applicable when examining axillary fossae to search for breast cancer metastases in the lymph nodes. This, in turn, distinguishes the method from mammography.
- A biopsy method helps to analyze the cellular composition, to distinguish a benign tumor process from a malignant one . It is carried out both by itself and under the supervision of ultrasound or mammography. Thanks to the method of puncture biopsies, it is possible to detect early cancer when there is no metastasis and palpable formations - that is, when neither doctors, nor women, nor other methods can detect it.
- Ultrasound diagnostics and its varieties (Elastography) is a method for examining soft tissues, but ultrasound does not determine calcifications and bone removal, therefore, it is used in combination with other research methods. Recommended for patients aged 18 to 45 years.
- MRI or magnetic resonance imaging is the most informative non-invasive diagnostic method, as it allows you to layer-by-layer examine the compaction images. However, due to the high cost of the study, it is carried out in exceptional cases.
- A radioisotope study is carried out by introducing radioisotopes into the bloodstream and, using an X-ray, determine the place of their accumulation (often radioisotopes tend to accumulate in tumors, depending on its characteristics of blood supply and hormonal activity).
- Puncture is an invasive diagnostic method that allows you to send part of the tissue seal for histological examination, to determine the type of cells that form this seal (if necessary, performed by an oncologist, including the district counseling in our clinic).
- General clinical examination methods (blood tests for hormones, a general blood test, etc.). The type of examination and its need is determined by your consulting doctor.
RISK FACTORS
There is a list of risk factors that affect the likelihood of a tumor, however, some are diagnosed with the disease in the absence of these factors, while others remain healthy if many of them are present. However, scientists still associate the development of breast cancer with certain circumstances:
- elderly age
- uncontrolled use of hormonal drugs
- breast injuries
- history of breast cancer
- a diagnosed breast cancer in a relative
- exposure to radiation, electromagnetic fields, microwave
- overweight, hypertension
- early onset of menstruation and later on - menopause
- absence of children or late birth (after 35 years) first birth
- abortion of the first pregnancy
- refusal of breastfeeding
- smoking and alcohol abuse
- diabetes mellitus, hypothyroidism
- Scheduled work with night shifts.
Stages of the disease
The first stage of the disease is a single tumor up to 2 cm in size, which does not have regional metastases. They are located in the lymph nodes, in the immediate vicinity of the affected organ - in the axillary fossa.
The second stage of the disease - the tumor is small, up to 2 cm or slightly larger, but often having a single metastasis in the axillary fossa. The more cancer is in the body, the more actively its harmful cells travel through our body. And they can be fixed in any of its organs. So cancer metastasizes.
The third stage of the disease is more diverse. It can be a small tumor, not reaching 3-4 cm, but having multiple metastases in the armpit. In some forms, the entire mammary gland is affected, and the cancer is not palpable. Or a nodular tumor from 5-10 cm in size is also the third stage of the disease.
The fourth stage of the disease - the most dangerous stage - a tumor of any size, with metastases to other organs and tissues: bones, liver, lungs, brain. This stage of cancer most often makes doctors powerless.
Breast Cancer Prevention
Since cancer is a multifactorial disease for prevention, you should know the following:
-
Perform a self-examination of the mammary glands in the first phase of the menstrual cycle.
- Visit your gynecologist or examination room regularly (mammologist if necessary).
- Do not abuse hormonal drugs of emergency contraception (postinor, escapel).
- If possible, continue breastfeeding for as long as possible.
- Control your weight and physical activity.
- Get rid of bad habits (smoking, excessive drinking of coffee).
- Balance your sex life.
Try to prevent situations that cause chronic stress.
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AMAZING WONDERS OF Gooseberry ON Amyloidosis
By stephany On 07/05/2020
Though gooseberry can not cure amyloidosis, it is a very effective herb or fruit to add to your diet. It's antioxidant property can suppress the progression of AApoAII amyloid deposition in the improved microenvironment of tissues and the effect may be related to the levels of oxidative stress in local tissues.
Amyloidosis is a rare systemic disease. In most patients, it has a secondary nature. In residents of the Mediterranean, as well as people of Jewish and Armenian nationality, the disease is due to a genetic predisposition. Why does this occur?
Various proteins can cause amyloid deposits. However, there is a group of proteins under the influence of which there is a serious violation of the activity of internal organs. Amyloids can accumulate both in a separate area of the body and throughout the body. The reasons for the development of amyloidosis depend on its type.
Nonetheless, after 25 years of research, the experts of africandoctor have discovered the best home remedy against amyloidosis. It is effective and affordable.
HERBAL TEA FOR AMYLOIDOSIS
Our treatment is not intended to completely treat the disease but rather to slow its progression and relieve the various symptoms of the disease. Indeed the natural remedy that we offer consists of plants with anti-inflammatory properties. It will also purify your blood and its diuretic properties will be beneficial to you if you have a disease of the kidneys, lymph nodes and spleen. For people suffering from affection to the nervous and cardiovascular system these plants will restore the functioning of these different systems. Our treatment is an all in one for the treatment of amyloidosis.
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Futhermore, other reasons for the development of this disease may lie in:
- deposition of beta-2-microglobulin in the blood;
- hemodialysis for more than 5 years;
- renal failure.
Most of all, joints, bones, and tendons suffer from this type of disease.
GOOSEBERRY AND AMYLOIDOSIS
ARE GOOSEBERRIES GOOD FOR THIS DISEASE?
Polyphenols in gooseberries, is another type of antioxidant that may also help prevent Alzheimer's by removing the build-up of toxins in cells. Gooseberries are great for amyloidosis because of its properties and effect on memory loss and toxins. Hence, Diuretic properties and hydration: Gooseberry has diuretic properties. A diuretic is a substance that increases the production of urine, which tends to flush out toxins, excess water and salts from the body. Removal of toxins also helps the body retain water and this aids in hydration.
GOOSEBERRY VS AMYLOIDOSIS
Gooseberry is a popular berry used in herbal treatment. It is the nature’s richest source of vitamin C and forms a part of Rejuvenation therapy or Rasayana therapy. This wonderful fruit has innumerable properties and works on several ailments. It provides nutrition to the body and effectively eliminates toxins from the body. It is used in fresh and dried forms.
HOW TO USE: SIMPLY ADD IT TO YOUR DAILY DIET
HOW TO MAKE GOOSEBERRY JUICE
Ingredients needed:
- Gooseberry
- Sugar or honey
- Water
Machinery requirements:
- Mixer Jar
- Blender
- Strainer
How to prepare:
- Transfer the chopped gooseberry into a mixer jar.
- Add ½ cup of water to ease the process of blending.
- Blend till the mixture of Indian gooseberry juice for detox is smooth.
- Strain using a strainer.
- Serve amla juice immediately.
GENARAL BENEFITS OF AMYLOIDOSIS
- It is higly nutritious
Just 1 cup (150 grams) of gooseberries contains:
- Protein
- Fat
- Carbs
- Fiber
- Vitamin C
- Vitamin B5
- Vitamin B6
- Copper
- Manganese
- Potassium
- It is high in fiber and low in calories
- It is rich in anti-oxidants
- It helps to control blood sugar level
- It is great with brain functioning
IS THERE ANY SIDE EFFECT OF THIS FRUIT?
Unfortunately, YES. Bleeding disorders is one of the negative effect of gooseberry, it increases the risk of bleeding or bruising in some people. If you have a bleeding disorder, use gooseberry with caution.
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HERBS TO DETOXIFY YOUR BODY AGAINST AMYLOIDOSIS: HOME REMEDY
By stephany On 07/05/2020
Amyloid deposits in the kidneys make it hard for them to do this job. When your kidneys do not work properly, water and dangerous toxins build up in your body. Furthermore, Toxic beta-amyloid is a distinguishing hallmark of Alzheimer's disease. But not all forms of beta-amyloid are toxic.
HERE ARE HOME REMEDIES TO GET RID OF THIS TOXINS!!! HELP YOUR KIDNEY FUNCTION PROPERLY DESPITE AMYLOIDOSIS.
1. HERBAL TEA FOR AMYLOIDOSIS
Our treatment is not intended to completely treat the disease but rather to slow its progression and relieve the various symptoms of the disease. Indeed the natural remedy that we offer consists of plants with anti-inflammatory properties. It will also purify your blood and its diuretic properties will be beneficial to you if you have a disease of the kidneys, lymph nodes and spleen. For people suffering from affection to the nervous and cardiovascular system, these plants will restore the functioning of these different systems. Our treatment is an all in one for the treatment of Amyloidosis.
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contact/WhatsApp: +22990431725
2. Terminalia chebula
It is a commonly used herb in India for relieving constipation. Many herbal formulations meant for treating constipation have this herb as one of the components. It acts very effectively and mildly on the stomach. It strengthens the digestive system and improves its functioning. It helps to clear blockages in the stomach.
3. Gooseberry
Gooseberry is a popular berry used in herbal treatment. It is the nature’s richest source of vitamin C and forms a part of Rejuvenation therapy or Rasayana therapy. This wonderful fruit has innumerable properties and works on several ailments. It provides nutrition to the body and effectively eliminates toxins from the body. It is used in fresh and dried forms.
4. Terminalia bellerica
It is helpful in eliminating excess fat from the body. It improves the functioning of the liver and increases the count of red blood cells. It is a rejuvenator and a laxative herb. It helps to relieve constipation. Its anthelmintic properties help to expel parasitic worms from the stomach. It also helps to prevent premature graying of hair. It is also efficient in controlling bleeding in the sputum and eases brancho-spasm. It improves the immunity function of the body and is helpful in maintaining the balance of blood pressure and cholesterol. Its paste can be applied to eyelids to cure conjunctivitis. The paste is also useful in treating swollen and inflamed painful parts. It is helpful in arresting bleeding of wounds.
5. Mixture of the following in powdered form
- Ashwagandha
- Methi
- Suranjaan
- Gorakhmundi
- Haridra
- Sonth
These herbs are used to manage the amyloidosis. Anti-inflammatory action of these herb help to reduces inflammation. Moreover this herbal powder helps to overcome the weakness and provides energy and stamina to the body.
How to use – 1 teaspoonful two times a day, with plain water, half an hour after meals.
6. Aloe Vera
This herb has great medicinal importance in traditional medicine. It helps to maintain the overall good health of body. It helps to enhance the overall functioning of all the organs. It possesses the high amounts of anti-oxidant which help in the removal of toxins from the body. In the problem of amyloidosis, it helps to flush out the proteins. Moreover this herb is quite useful in managing the symptoms of amyloidosis such as weakness, fatigue and shortness of breath etc. Aloe vera extracts aregreat for amyloidosis.
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Potassium , starch and vitamin C for amyloidosis
By stephany On 07/05/2020
Amyloidosis is a disease characterized by impaired protein metabolism, as a result of which a protein-polysaccharide complex (amyloid) is formed and accumulates in the tissues. However, there are useful foods that can aid in managing this disease which is going to list in this article.
Nonetheless, after 25 years of research, the experts of Africandoctor have discovered the best home remedy against amyloidosis. It is effective and affordable.
HERBAL TEA FOR AMYLOIDOSIS
Our treatment is not intended to completely treat the disease but rather to slow its progression and relieve the various symptoms of the disease. Indeed the natural remedy that we offer consists of plants with anti-inflammatory properties. It will also purify your blood and its diuretic properties will be beneficial to you if you have a disease of the kidneys, lymph nodes, and spleen. For people suffering from affection to the nervous and cardiovascular system, these plants will restore the functioning of these different systems. Our treatment is an all in one for the treatment of amyloidosis.
CLICK ON THIS LINK TO DISCOVER THE PRODUCT
We deliver to the world!!!
contact/WhatsApp: +22990431725
Useful food for amyloidosis
In the presence of the disease, a diet should be followed in which the body is saturated with potassium, starch, and vitamin C.
Potassium-rich foods:
- vegetables (cucumbers, potatoes, zucchini, parsnips, carrots, green leafy vegetables);
- legumes, including peanuts;
- honey and bee products, especially pollen;
- Apple vinegar;
- mushrooms;
- fresh fruits (watermelon, oranges, melons, bananas);
- dried fruits (raisins, apricots, plums, figs);
- rye bread, wheat bran;
- nuts (cedar, almonds);
- wheat and oatmeal;
- products of animal origin: beef, fish, liver, dairy products;
- tea.
Starchy foods include:
- porridge: oatmeal, buckwheat, millet, wheat and rice (brown), also barley and semolina;
- bakery and pasta products, oatmeal cookies;
- cereals: rye, wheat, oats, maize;
- beans and peas;
- horseradish roots and ginger.
- Small amounts of starch are contained in pumpkin, carrots, tomatoes, garlic, cabbage, radishes, parsley, so we will not focus on them.
Foods That Give Your Body Vitamin C:
- berries: rose hips, peel, black currant, viburnum, blackberry, strawberry, herb eagle nail;
- citrus fruits;
- kiwifruit ;
- all kinds of cabbage;
- sweet and hot peppers;
- horseradish root;
- young garlic;
- spinach.
Dangerous and harmful foods in amyloidosis:
As the potassium is washed away from the confectionery, it should not be consumed. Do not take products containing caffeine, alcoholic beverages. Excessive physical activity and stress also wash the substance out of the body.
It is necessary to limit protein foods:
- tofu;
- egg white;
- desserts and small sweets type "kisses";
- soy milk;
- lean beef and veal;
- rabbit and chicken;
- marine products;
Limit the use of salt and salty foods, especially by people with kidney and heart problems.
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GET RID OF AMYLOIDOSIS IN LESS THAN THREE MONTHS: NATURAL MEANS
By stephany On 07/05/2020
Do you have amyloidosis and looking for who to run to? If yes, you have run to the right place. Here we will offer you the best treatment to deal with amyloidosis symptoms. But firstly, why not medical treatment? Read to the end to discover the best treatment for you.
Can amyloidosis be treated?
Amyloidosis can and should be treated, but the management depends on the type of disease. In the case of AA amyloidosis, the inflammation that caused it should be combated. In AL amyloidosis, chemotherapy is the treatment of choice.
WHAT IS THE BEST TREATMENT FOR AMYLOIDOSIS?
The treatment of amyloidosis is based on the form of the disease.
HERBAL TEA FOR AMYLOIDOSIS
Our treatment is not intended to completely treat the disease but rather to slow its progression and relieve the various symptoms of the disease. Indeed the natural remedy that we offer consists of plants with anti-inflammatory properties. It will also purify your blood and its diuretic properties will be beneficial to you if you have a disease of the kidneys, lymph nodes, and spleen. For people suffering from affection to the nervous and cardiovascular system, these plants will restore the functioning of these different systems. Our treatment is an all in one for the treatment of amyloidosis. This treatment is more affordable than medical treatment.
CLICK ON THIS LINK TO DISCOVER THE PRODUCT
We deliver to the world!!!
contact/WhatsApp: +22990431725
OBJECTIVE OF MEDICAL Treatment of amyloidosis
Treatment of amyloidosis is two-fold. On the one hand, it involves alleviating symptoms to maintain a good quality of life for patients, on the other - therapy to inhibit the production of amyloid protein. The treatments currently proposed can change the natural course of the disease, provided they are implemented before irreversible organ damage occurs. Early diagnosis, proper selection of amyloid, inclusion of appropriate treatment of the underlying disease adapted to the risk level, close observation and supportive treatment are crucial for the effectiveness of therapy. The localized form of amyloidosis requires radiotherapy or surgery, generalized amyloidosis and systemic treatment.
TREATMENT OF AL AMYLOIDOSIS
For the most effective but also the most aggressive method of treatment - high-dose chemotherapy followed by autologous bone marrow stem cell transplantation ( ASCT)) - patients are eligible in good general condition without serious heart damage. In some cases, if there is an increased percentage of plasmacytes in the bone marrow> 10%, treatment starts with chemotherapy, and the ASCT procedure begins after a few months, after reducing the infiltration in the bone marrow.
Other drugs used to date for myeloma are also being studied in amyloidosis. These include, but are not limited to, immunomodulatory drugs such as lenalidomide. Caution in their introduction is caused, among others, by a higher risk of side effects than in myeloma.
WHAT IF THE TREATMENT DOESN'T WORK OR THE DISEASE RECURS?
For relapsed or refractory disease, various myeloma therapy regimens are adapted. These include combinations based on bortezomib, lenalidomide, bendamustine, as well as new drugs such as daratumumab, pomalidomide and ixazomib. The latest drugs are only available as part of clinical trials.
TREATMENT OF OTHER FORMS OF AMYLOIDOSIS
The drug directly affecting the accumulation of deposits in AA amyloidosis is currently in the sphere of research. The greatest emphasis in therapy is put on removing the cause of the formation of SAA amyloid, which is chronic inflammation.
In amyloidosis AF, so-called drugs are being tested. stabilizers of amyloid proteins (diflunisal, tafamidis), preventing the transformation of the correct TTR protein into amyloid. In some situations, liver transplantation is considered.
The management of senile amyloidosis is mainly aimed at alleviating its symptoms, but some efficacy of diflunisal or tafamidis is also observed.
For cardiac involvement in AF and AS amyloidosis, doxycycline is also given.
ORGAN TRANSPLANTATION
Organ transplantation in place of those irreversibly damaged by amyloidosis is technically possible. However, it is considered when at least a very good partial hematological response was obtained after the hematological treatment described briefly above (VGPR). Otherwise, the risk that the transplanted organ would be quickly destroyed by the disease is too high. Heart transplantation is a serious procedure, it can only be offered to young patients. Kidney transplants are performed much more often. Attempts are also being made to liver transplantation, but here, apart from congenital amyloidosis, the effects are much worse.
HOW IS AMYLOIDOSIS DETECTED?
Amyloidosis assumed on the basis of clinical and laboratory data must be confirmed morphologically by the detection of amyloid in tissue biopsies.
If AL-type amyloidosis is suspected, bone marrow puncture is recommended. The counting of plasma cells and the staining of punctate on amyloid allows not only to diagnose amyloidosis, but also to differentiate the primary and associated with myeloma variants of AL-amyloidosis. A positive result of a study of bone marrow on amyloid was observed in 60% of patients with AL-amyloidosis.
A simple and safe diagnostic procedure is an aspiration biopsy of subcutaneous fat, in which amyloid is detected in 80% of cases of AL-amyloidosis. The advantages of this procedure, in addition to informativeness, also include the rarity of bleeding, which makes it possible to use this method in patients with blood coagulation disorders (patients with primary amyloidosis often have a coagulation factor X deficiency in which hemorrhages can develop).
Most often, for the diagnosis of different types of amyloidosis, a biopsy of the mucous membrane of the rectum, kidney, and liver is performed. A biopsy of the mucous and submucous layers of the rectum allows the detection of amyloid in 70% of patients, and a kidney biopsy in almost 100% of cases. In patients with carpal tunnel syndrome, amyloid examination should be performed on tissue removed during carpal tunnel decompression.
Biopsy material for the detection of amyloid must be stained with Congo red, followed by microscopy in polarized light to detect birefringence. Modern morphological diagnosis of amyloidosis includes not only detection, but also typing of amyloid, since the type of amyloid determines the therapeutic tactics. For typing, a sample with potassium permanganate is often used. When treating Congo-stained red preparations with a 5% potassium permanganate solution, the AA-type amyloid loses its color and loses the birefringence property, while the AL-type amyloid retains them. The use of alkaline guanidine makes it possible to more accurately differentiate AA and AL amyloidosis.
The most effective method for typing amyloid is an immunohistochemical study using antisera to the main types of amyloid protein (specific antibodies against AA protein, immunoglobulin light chains, transthyretin and beta-2-microglobulin).
HOW LONG CAN YOU LIVE WITH THIS DISEASE?
With untreated AL amyloidosis, survival is short, about a year, and up to six months with severe heart damage. It is doubled when used. It should be remembered that the earlier the diagnosis is made and the treatment is initiated, the greater the chances of a long survival.
In AA amyloidosis, the average survival exceeds 10 years. Extinguishing the inflammation stops or slows down the process of amyloid deposition, which significantly improves the prognosis.
In amyloidosis AF, the average survival is estimated at 5-15 years from the time of diagnosis.
Our expert's opinion: A balanced diet is very important for the body's energy supply. Although amyloid is a protein, changing the amount of protein consumed does not affect the course of the disease. However, you may need a special diet depending on the symptoms and organs involved (e.g. kidney or liver damage).
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